The most abundant cell type in the bronchus is fibroblasts. Human Bronchial Fibroblasts (HBF) display a mesenchymal stem cell phenotype and their principle function is to produce type III collagen, elastin, and proteoglycans of the extracellular matrix. Bronchial fibroblasts play an important role in the repair and remodeling processes following injury. The controlled accumulation of fibroblasts to sites of inflammation is crucial for effective tissue repair after injury. Either inadequate or excessive accumulation of fibroblasts can result in abnormal tissue function. For example, the excess fibroblast proliferation and collagen secretion that occurs from bronchial subepithelial fibrosis can result in airway obstruction and bronchial hyper-responsiveness. HBF cultures provide an in vitro model in the pathophysiological studies of bronchial disorders; such as bronchiectasis, bronchiolitis or bronchopulmonary dysplasia.
Innoprot/人支气管成纤维细胞/P10563
市场价：
¥1500000.00
美元价：
750000.00
产品分类：
冰箱/液氮罐
公司分类：
Liquid_nitrogen_tank
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Product Description
- Specifications
- Characterization
- Similars
- Publications
- Technical Resources & Protocols
- Reference: P10563
- Size/Quantity: 5x105 cells / vial
- Product Use: For research use only
- Shipping Conditions: Dry Ice
- Data Sheet - Cell Cuture Manual
品牌介绍
Innoprot是一家生物技术公司，成立于2007年，是巴斯克地区大学的附属公司。Innoprot提供产品和技术，用于在药物发现和开发中对基于细胞的测定进行多路复用，包括原代细胞，永生细胞系和重组细胞系。凭借专有的GPCR筛选技术，Innoprot能够鉴定具有最高效力的化合物，同时避免了不良副作用。Innoprot还担任CRO，提供针对GPCR，纤维化和神经退行性疾病（例如阿尔茨海默氏病，帕金森氏病或ALS）的筛查服务。Inno prot的私人员工将药物发现技术领域的经验与制药服务提供商广泛的职业道路相结合。
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