Human Epidermal Melanocytes are neural crest-origin cells that produce melanin via melanogenesis. Melanocytes localize to several tissues including the epidermis, eye, inner ear and leptomeninges. Dysregulation of melanocyte migration, proliferation, or survival during embryonic development thus causes congenital disorders in those tissues. In the bottom layer of skin epidermis, melanocytes synthesize and transfer dark-colored melanin to surrounding keratinocytes to give skin pigmentation. Melanin also blocks UV-B light to protect the hypodermis from solar exposure-induced photodamage. Progress in culture techniques, along with an improved understanding of melanocyte biology, has led to a successful culture system to model melanomas, inner ear homeostasis, vitiligo, and mitochondrial dysfunction in Duchenne Muscular Dystrophy.
Innoprot/人表皮黑素细胞/P10853
市场价：
¥1120000.00
美元价：
560000.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Product Description
- Specifications
- Characterization
- Similars
- Publications
- Technical Resources & Protocols
- Reference: P10853
- Size/Quantity: 5x105 cells / vial
- Product Use: For research use only
- Shipping Conditions: Dry Ice
- Data Sheet - Cell Culture Manual
品牌介绍
Innoprot是一家生物技术公司，成立于2007年，是巴斯克地区大学的附属公司。Innoprot提供产品和技术，用于在药物发现和开发中对基于细胞的测定进行多路复用，包括原代细胞，永生细胞系和重组细胞系。凭借专有的GPCR筛选技术，Innoprot能够鉴定具有最高效力的化合物，同时避免了不良副作用。Innoprot还担任CRO，提供针对GPCR，纤维化和神经退行性疾病（例如阿尔茨海默氏病，帕金森氏病或ALS）的筛查服务。Inno prot的私人员工将药物发现技术领域的经验与制药服务提供商广泛的职业道路相结合。
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