Endothelial cells lining the microvasculature play a critical “gatekeeper” role in the inflammatory process through their ability to recruit circulating immune cells into tissues and foci of inflammation. Human Esophageal Microvascular Endothelial Cells (HEsMEC) exhibit a strong inflammatory immune response to LPS, cytokines, and pH exposure, thus playing a critical regulatory role in esophageal inflammation. When exposed to acidic pH, HEsMEC express certain proteins, such as VCAM-1, but not others, such as ICAM-1. This expression pattern could play a role in the cellular response triggered by gastroesophageal reflux disease. HEsMEC cultures have enabled scientists to observe leukocyte binding, upregulation of cell adhesion molecules, and other cellular responses to LPS, cytokines and pH exposure. HEsMEC are intrinsically different from lower gastrointestinal endothelial cells.
Innoprot/人食管微血管内皮细胞/P10764
市场价：
¥1670000.00
美元价：
835000.00
产品分类：
原代细胞
公司分类：
Primary_cell
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Product Description
- Specifications
- Characterization
- Similars
- Publications
- Technical Resources & Protocols
- Reference: P10764
- Size/Quantity: 5x105 cells / vial
- Product Use: For research use only
- Shipping Conditions: Dry Ice
- Data Sheet - Cell Cuture Manual
品牌介绍
Innoprot是一家生物技术公司，成立于2007年，是巴斯克地区大学的附属公司。Innoprot提供产品和技术，用于在药物发现和开发中对基于细胞的测定进行多路复用，包括原代细胞，永生细胞系和重组细胞系。凭借专有的GPCR筛选技术，Innoprot能够鉴定具有最高效力的化合物，同时避免了不良副作用。Innoprot还担任CRO，提供针对GPCR，纤维化和神经退行性疾病（例如阿尔茨海默氏病，帕金森氏病或ALS）的筛查服务。Inno prot的私人员工将药物发现技术领域的经验与制药服务提供商广泛的职业道路相结合。
联络我们
