Human Pancreatic Stellate Cells (HPanSteC) are the main fibroblastic cells of the pancreas. HPaSteC are responsible for the synthesis and the degradation of the extracellular matrix proteins that promote tissue repair. They are present adjacent to pancreatic acinar cells and around small pancreatic ducts and blood vessels. Upon activation, HPanSteC assume myofibroblast-like morphology and secrete excessive amounts of extracellular matrix proteins. This proces can lead to desmoplasia in chronic pancreatitis and adenocarcinoma. HPanSteC can also act as progenitor cells, immune cells, and intermediaries in exocrine pancreatic secretion. Additionally, HPanSteC stimulate pancreatic cancer proliferation, inhibit apoptosis, and enhance angiogenesis. HPaSteC are the ideal model for studying pancreatic tumor formation and also to develop novel therapies for treatment of chronic pancreatitis and adenocarcinoma.
Innoprot/人胰腺星状细胞/P10474
市场价：
¥1590000.00
美元价：
795000.00
产品分类：
细胞增殖
公司分类：
cell_proliferation
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Product Description
- Specifications
- Characterization
- Similars
- Publications
- Technical Resources & Protocols
- Reference: P10474
- Size/Quantity: 5x105 cells / vial
- Product Use: For research use only
- Shipping Conditions: Dry Ice
- Data Sheet - Cell Cuture Manual
品牌介绍
Innoprot是一家生物技术公司，成立于2007年，是巴斯克地区大学的附属公司。Innoprot提供产品和技术，用于在药物发现和开发中对基于细胞的测定进行多路复用，包括原代细胞，永生细胞系和重组细胞系。凭借专有的GPCR筛选技术，Innoprot能够鉴定具有最高效力的化合物，同时避免了不良副作用。Innoprot还担任CRO，提供针对GPCR，纤维化和神经退行性疾病（例如阿尔茨海默氏病，帕金森氏病或ALS）的筛查服务。Inno prot的私人员工将药物发现技术领域的经验与制药服务提供商广泛的职业道路相结合。
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