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当前位置: 首页 > 产品中心 > serum > Innoprot/永生化人膀胱平滑肌细胞/P10951-IM
商品详细Innoprot/永生化人膀胱平滑肌细胞/P10951-IM
Innoprot/永生化人膀胱平滑肌细胞/P10951-IM
Innoprot/永生化人膀胱平滑肌细胞/P10951-IM
商品编号: P10951-IM
品牌: Innoprot
市场价: ¥39.00
美元价: 19.50
产地: 美国(厂家直采)
公司:
产品分类: 血清
公司分类: serum
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

The urinary bladder is a hollow organ which comprises mainly of smooth muscle cells (SMC). The relaxation and contraction of urinary bladder smooth muscle allows the bladder to store and void urine, respectively. Phenotypic modulation of bladder SMC and the expression of inducible nitric oxide synthase are related with various pathological conditions, including bladder dysfunction. Hypoxia inhibits human bladder SMC proliferation upregulating also survival factors such as HIF1 alpha and VEGF. The secretory phenotype of the bladder SMC extracellular matrix depends on the frequency of mechanical deformation experienced by these cells. SMC proliferation is a major contributing factor to the development and progression of a variety of diseases. As a result, understanding SMC changes during the genesis and maintenance of disease is vital to the development of therapeutic approaches. Immortalized Human Bladder Smooth Muscle Cells are also useful tools to develop disease models for High Throughput and High Content Screening.

  • Reference: P10951-IM
  • Size/Quantity: 1x106 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice
    • Technical Sheet
    品牌介绍
    Innoprot是一家生物技术公司,成立于2007年,是巴斯克地区大学的附属公司。Innoprot提供产品和技术,用于在药物发现和开发中对基于细胞的测定进行多路复用,包括原代细胞,永生细胞系和重组细胞系。凭借专有的GPCR筛选技术,Innoprot能够鉴定具有最高效力的化合物,同时避免了不良副作用。Innoprot还担任CRO,提供针对GPCR,纤维化和神经退行性疾病(例如阿尔茨海默氏病,帕金森氏病或ALS)的筛查服务。Inno prot的私人员工将药物发现技术领域的经验与制药服务提供商广泛的职业道路相结合。